Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare myeloid malignancy characterized by the aggressive proliferation of precursors of plasmacytoid dendritic cells that frequently involves the bone marrow, skin, central nervous system, and other organs and tissues. In an article published by Pollyea et al in JNCCN–Journal of the National Comprehensive Cancer Network, the authors review the diagnosis and management of BPDCN as outlined in the NCCN Guidelines for acute myeloid leukemia (AML).
